Prostaglandins are nature’s universal signalers, self-regulating every physiological function, and defined as “a generalized physiological control mechanism”. They are minute, ephemeral, and powerful, and extraordinarily sensitive to all forms of stress. whether mechanical, physical, chemical, biological, or interpersonal. When enzymes increase prostaglandin production...

Stimulating defective immune function to perform efficiently is a desirable approach to defeating pathogens. Such stimulation is represented as unavailable, while in truth the immunostimulating properties of lithium and antidepressants were documented many years ago.[1-4] A therapeutic claim is reinforced when the mechanism is known. Prostaglandins, when produced excessively,...

Depression predisposes to panoply of infectious, autoimmune, cardiovascular and neurodegenerative disorders, and to cancer.  Relatively recent additions include diabetes mellitus, Parkinson’s, Alzheimer’s and Huntington’s diseases, seizure disorders, chronic obstructive lung disease, congestive heart failure, and cancer. The intensity of depression appears to correlate...

Dead crabs and fish wash up on shores, birds drop from the skies, and cows flop in the fields. One hundred and fifty one years ago, Charles Darwin and Alfred Russel Wallace knew that birds dropping from the skies, dead fish and crabs washing up from the sea, and cows flopping in the fields, are nature’s spectacular staging of what Darwin termed natural selection. Darwin...

Stimulating defective immune function to perform efficiently is a desirable approach to defeating pathogens. Such stimulation is represented as unavailable, while in truth the immunostimulating properties of lithium and antidepressants were documented many years ago.[1-4]  A therapeutic claim is reinforced when the mechanism is known. Prostaglandins, when produced excessively,...

The Breakthrough: (Abstract) Adult patients with Down syndrome show psychological symptoms and early senility. Improving their environment and dealing with their complaints and stress should first address their behavioral problems, such as self-injury, depression, aggression and outbursts. Pharmacological treatment may also be tried for behavioral disorders. Individuals...